| Cat. No. |
Product Name |
Information |
| PC-45175 |
Dexpramipexole
Dopamine receptor agonist
|
Dexpramipexole ((R)-Pramipexole) is a partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively. |
| PC-45174 |
Dexpramipexole dihydrochloride
Dopamine receptor agonist
|
Dexpramipexole dihydrochloride ((R)-Pramipexole) is a partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively. |
| PC-45173 |
Pramipexole dihydrochloride
Dopamine receptor agonist
|
Pramipexole dihydrochloride is a partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively. |
| PC-46022 |
Rotigotine hydrochloride
Dopamine receptor agonist
|
Rotigotine hydrochloride is a non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM), has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor. |
| PC-45959 |
Rotigotine
Dopamine receptor agonist
|
Rotigotine is a non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM), has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor. |
| PC-44374 |
rac-Rotigotine hydrochloride
Dopamine receptor agonist
|
rac-Rotigotine hydrochloride is a non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM), has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor. |
| PC-28438 |
Glovadalen
D1 PAM
|
Glovadalen (UCB0022) is a potent, selective, brain-penetrant and orally available dopamine D1 receptor (D1R) positive allosteric modulator (PAM). |
| PC-28317 |
S33084
D3R antagonist
|
S33084 is a potent, selective dopamine D3 receptor (D3R) antagonist with pKi of 9.2 (hD2), displays >100-fold selectivity over D4. |
| PC-28316 |
Nafadotride
D3R antagonist
|
Nafadotride is a selective dopamine D3 receptor (D3R) antagonist, displays a high affinity for dopamine D2 and D3 receptors, but a low affinity for doparnine D1 and D4. |
| PC-28315 |
L-741626
D2R antagonist
|
L-741626 is a potent, selective dopamine D2 receptor (D2R, DRD2) antagonist with Ki of 2.4 nM, shows 45-80 fold selectivity over D3 and D4 receptors. |
| PC-28243 |
Chlorpromazine hydrochloride
D2R antagonist, Endocytosis inhibitor
|
Chlorpromazine hydrochloride (CPZ) is a phenothiazine antipsychotic that acts as a competitive antagonist at the D2 receptor, also exhibits antagonist activity at serotonin (5-HT) receptors 5-HT2A and 5-HT2C receptors also inhibits clathrin-mediated endocytosis. |
| PC-28242 |
Chlorpromazine
D2R antagonist, Endocytosis inhibitor
|
Chlorpromazine (CPZ) is a phenothiazine antipsychotic that acts as a competitive antagonist at the D2 receptor, also exhibits antagonist activity at serotonin (5-HT) receptors 5-HT2A and 5-HT2C receptors also inhibits clathrin-mediated endocytosis. |
