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18085-97-7 Jaceosidin (4'-Demethyleupatilin, Jaseocidin) is a trihydroxyflavone that exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties; promotes angiogenesis via activation of VEGFR2/FAK/PI3K/AKT/NF-κB signaling pathways in endothelial cells; shows selective suppression of proliferation (IC50 = 82.1 μM in HSC-3 cells and 97.5 μM in Ca9.22 cells) and accumulation of cells at the sub-G1 stage of the cell cycle, induces apoptotic cell death and inhibits the Akt pathway in oral cancer cells.


22368-21-4 Eupatilin (NSC 122413, Stillen) is a pharmacologically active flavone derived from Artemisia plants, possess anti-inflammatory, anti-oxidative and anti-cancer activities; induces cell cycle arrest in ras-transformed human mammary epithelial cells; attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities; inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling.


20784-50-3 Isobavachalcone (Corylifolinin, Isobacachalcone) is a chalcone constituent of Angelica keiskei that can induce apoptosis in several cancer cells, also shows activity against multidrug-resistant (MDR) Gram-negative bacterial isolates; significantly reduces pro-caspase-3 and pro-caspase-9, and subsequently increases the level of cleaved caspase-3 and cleaved caspase-9 in neuroblastoma cell lines also exhibiting deletions of the major efflux pump components (AcrAB, TolC).

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