| Cat. No. |
Product Name |
Information |
| PC-49290 |
Tideglusib
GSK-3 inhibitor
|
Tideglusib (NP031112, NP-12) is a potent and irreversible small molecule glycogen synthase kinase 3 (GSK-3) inhibitor with IC50 of 60 nM. |
| PC-72725 |
COB-187
GSK-3 inhibitor
|
COB-187 (COB187) is a highly potent and selective inhibitor of GSK-3 with IC50 of 22/11 nM against GSK-3α/GSK-3β. |
| PC-63311 |
BRD0705
|
BRD0705 is a potent, paralog-selective GSK3α inhibitor with IC50 of 66 nM, 8-fold selectivity over GSK3β (IC50=515 nM). |
| PC-42827 |
SB 216763
GSK-3 inhibitor
|
SB 216763 is a potent, selective, ATP competitive and cell permeable inhibitor GSK-3 with Ki of 9 nM (GSK-3α), equally potent for GSK-3β. |
| PC-63153 |
1-Azakenpaullone
|
1-Azakenpaullone is an analog of kenpaullone and is a potent, selective GSK3β inhibitor with IC50 of 18 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=2.0 and 4.2 uM). |
| PC-60431 |
9-ING-41
GSK-3β inhibitor
|
Elraglusib (9-ING-41) is a novel potent, selective GSK-3β inhibitor with IC50 of 0.7 uM. |
| PC-42428 |
CHIR-99021
|
Laduviglusib (CHIR-99021, CT99021) is a potent, specific GSK-3 inhibitor with IC50 of 5 nM and 10 nM for GSK3β and GSK3α, respectively. |
| PC-42628 |
AR-A014418
GSK-3β inhibitor
|
AR-A014418 is a potent, specific ATP-competitive inhibitor of GSK-3β with Ki/IC50 of 38/104 nM. |
| PC-45724 |
Indirubin-3|-monoxime
|
A potent GSK3β inhibitor with IC50 of 22 nM. |
| PC-20193 |
LY2090314
GSK-3 inhibitor
|
LY2090314 is a potent and selective ATP-competitive inhibitor of Glycogen synthase kinase-3 (GSK-3) with IC50 of 1.5/0.9 nM for GSK3α/GSK3β, respectively. |
| PC-20191 |
GSK3 inhibitor 117
GSK-3 inhibitor
|
GSK3 inhibitor 117 is a novel selective GSK-3 inhibitor, shows cytotoxicity against AML in vitro and in vivo. |
| PC-20114 |
GSK-3β inhibitor 47
|
GSK-3β inhibitor 47 is a potent, selective, brain-penetrant, orally bioavailable GSK-3β inhibitor with IC50 of 0.73 nM, inhibits phosphorylated tau with cell IC50 of 58 nM. |
