IRE1 (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofIRE1 IRE1

Cat. No.	Product Name	Information
PC-45337	APY29 IRE1 inhibitor	APY-29 is an allosteric modulator of IRE1α that inhibits IRE1α autophosphorylation with IC50 of 280 nM and activates IRE1α RNase activity.
PC-45674	4μ8C IRE1 inhibitor	4μ8C (4mu8C, IRE1 Inhibitor III) is a potent IRE1 endonuclease inhibitor, blocks substrate access to the active site of IRE1 and selectively inactivates both Xbp1 splicing and IRE1-mediated mRNA degradation.
PC-23681	1ACTA IRE1α S-nitrosylation inhibitor	1ACTA is a specific small molecule inhibitor of IRE1α S-nitrosylation, selectively prevents the NO-induced reduction of RNase activity.
PC-22296	IRE1α inhibitor 16 IRE1α inhibitor	IRE1α inhibitor 18 is a potent, selective and allosteric inhibitor of IRE1α endonuclease activity with enzyme IC50 of 13 nM, cellular IRE1α IC50 of 99 nM in XBP1-Luc cellular assays.

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