| Cat. No. |
Product Name |
Information |
| PC-43487 |
Montelukast sodium
LTD4 inhibitor
|
Montelukast sodium (MK0476, MK-0476) is a potent, selective, orally active leukotriene D4 receptor (LTD4) antagonist with Ki of 0.18 nM for guinea pig lung LTD4. |
| PC-61097 |
ONO 2050297
|
ONO 2050297 (ONO2050297) is potent, selective, dual CysLT1 and CysLT2 antagonist with IC50 of 17 and 0.87 nM, respectively. |
| PC-45294 |
Zafirlukast
CysLT1 antagonist
|
Zafirlukast (ICI-204219) is a potent, selective, orally active cysteinyl leukotriene 1 (CysLT1) receptor antagonist with IC50 of 14 nM in cell-based calcium mobilization assays. |
| PC-45775 |
MK-571 sodium salt
LTD4 inhibitor
|
MK-571 sodium is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM. |
| PC-21589 |
LY255283
BLT2 inhibitor
|
LY255283 is a selective, competitive antagonist of leukotriene B4 receptor (BLT2) with IC50 of 1 uM, 10-fold selective over BLT1 receptor. |
| PC-21194 |
U75302
LTB4 receptor 1 inhibitor
|
U75302 is a specific leukotriene B4 receptor 1 (LTB4 receptor 1, BLTR1, BLT1) inhibitor, effectively block LTB4 responses. |
| PC-20647 |
LY290154
LTD4/E4 antagonist
|
LY290154 is a leukotriene LTD4/E4 antagonist. |
| PC-49347 |
REV5901
Leukotriene Receptor inhibitor
|
REV 5901 (REV5901) is a competitive antagonist of peptidoleukotrienes with binding Ki of 0.7 uM (guinea pig lung membranes), also inhibits rat neutrophil 5-LO with IC50 of 0.12 uM. |
| PC-35978 |
Gemilukast
|
Gemilukast (ONO-6950, ONO6950) is a potent, orally active, dual CysLT1 and CysLT2 antagonist with IC50 of 1.7 and 25 nM against human CysLT1 and human CysLT2, respectively. |
| PC-43540 |
Nedocromil
|
Nedocromil (FPL59002) is a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes.. |
| PC-35285 |
HAMI3379
|
HAMI3379 (HAMI-3379) is a potent and selective antagonist of cysteinyl leukotriene 2 (CysLT(2)) receptor, inhibits LTD4- and LTC4-induced intracellular calcium mobilization withIC50 of 3.8 nM and 4.4 nM respectively. |
| PC-63302 |
Amelubant
|
Amelubant (BIIL284) is a potent, long-acting, orally active leukotriene B4 (LTB4) receptor antagonist, inhibits LTB4-induced mouse ear inflammation with ED50 of 0.008 mg/kg (p.o.). |
