| Cat. No. |
Product Name |
Information |
| PC-27032 |
nNOS-PDZ inhibitor N24
nNOS-PDZ inhibitor
|
nNOS-PDZ inhibitor N24 is a potent and selective small-molecule inhibitor of PDZ domain of neuronal nitric oxide synthase (nNOS-PDZ) with IC50 of 0.76 uM in FP assays. |
| PC-26110 |
MA48
CAPON inhibitor
|
MA48 is a small molecule CAPON (NOS1AP) binder (MST Kd=11.9 uM) that disrupts the CAPON-nNOS interaction in a cellular context. |
| PC-25145 |
SCR-4026
nNOS-PSD95 inhibitor
|
SCR-4026 is a small molecule inhibitor of nNOS-PSD95 interaction, disrupts nNOS-PSD-95 association with an IC50 of 6.3 μM in vitro. |
| PC-25066 |
Lubeluzole dihydrochloride
NOS inhibitor
|
Lubeluzole dihydrochloride is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway. |
| PC-25065 |
Lubeluzole
NOS inhibitor
|
Lubeluzole is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway. |
| PC-23980 |
MAC-3-190
nNOS inhibitor
|
MAC-3-190 is a potent, selective inhibitor of neuronal nitric oxide synthase (nNOS), inhibits the growth of metastatic melanoma, glioblastoma, and hepatocellular carcinoma in vitro and in vivo. |
| PC-23979 |
HH044
nNOS inhibitor
|
HH044 is a potent, selective inhibitor of neuronal nitric oxide synthase (nNOS) with Ki of 5 nM, >250-fold selective over iNOS and eNOS. |
| PC-23711 |
7-Nitroindazole (7-NI)
nNOS inhibitor
|
7-Nitroindazole (7-NI) is a selective and BBB-penatrable inhibitor of nNOS, inhibits the activity of central NOS with an IC50 of 0.47 μM in the cerebellum of mice, has anti-injurious and neuroprotective properties. |
| PC-20973 |
nNOS inhibitor 17
nNOS inhibitor
|
nNOS inhibitor 17 is a potent, selective neuronal nitric oxide synthase (nNOS) inhibitor with Ki of 15 and 19 nM for rat and human nNOS, respectively. |
