| Cat. No. |
Product Name |
Information |
| PC-35193 |
CAT639
iNOS inhibitor
|
CAT639 is an improved analog of ATV399 that exhibits improved β-cell viability and insulin secretion in the rat insulin-producing INS1E cells and primary rat dispersed islet cells, inhibits dimerization of iNOS. |
| PC-35192 |
ATV399
iNOS inhibitor
|
ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase 9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS. |
| PC-42897 |
GW274150
iNOS inhibitor
|
GW274150 is a potent and highly selective inhibitor of iNOS with IC50 of 1.4 uM, displays >200 fold selectivity over eNOS and nNOS (IC50>100 uM). |
| PC-42371 |
SDMA
Nitric oxide synthase inhibitor
|
SDMA (Symmetric dimethylarginine) is an arginine derivative and an endogenous inhibitor of nitric oxide (NO) synthase activity. |
| PC-62230 |
AR-C102222
iNOS inhibitor
|
AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively. |
| PC-62229 |
iNOS inhibitor 12
iNOS inhibitor
|
iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS. |
| PC-61062 |
nNOS-IN-25
nNOS inhibitor
|
nNOS-IN-25 is a potent, selective cell permeable neuronal nitric oxide synthase (nNOS) inhibitor with Ki of 30 nM. |
| PC-60993 |
ASP9853
iNOS inhibitor
|
ASP9853 (FR260330) is a potent, orally active iNOS inhibitor (IC50=10 nM, NO release DLD-1 cells) that prevents dimerization of iNOS, but has no effect on the expression or enzyme activity of iNOS. |
| PC-70228 |
1400W dihydrochloride
iNOS inhibitor
|
1400W dihydrochloride is a potent, selective inhibitor of iNOS with Ki of 7 nM. |
| PC-45544 |
L-NAME hydrochloride
NOS inhibitor
|
L-NAME hydrochloride is a widely used inhibitor of NO synthase (NOS) with IC50 of 70 uM for purified brain NOS. |
| PC-42163 |
IC87201
PSD-95/nNOS inhibitor
|
IC87201 (IC 87201) is a small molecule inhibitor of PSD-95/nNOS interaction with IC50 of 31 uM, without inhibiting nNOS catalytic activity. |
| PC-42162 |
ZL006
PSD95-nNOS inhibitor
|
ZL006 (ZL 006, ZL006) is a brain penetrant small molecule inhibitor of PSD-95/nNOS interaction that prevents glutamate-induced excitotoxicity and cerebral ischemic damage in vivo. |
