| Cat. No. |
Product Name |
Information |
| PC-27445 |
MDOLL-0591
CHIKV nsP3 inhibitor
|
MDOLL-0591 is a selective inhibitor targeting chikungunya virus (CHIKV) nsP3 macrodomain with IC50 of 10 uM, shows antiviral activity against CHIKV in cell culture. |
| PC-27376 |
GHP-88310
Orthoparamyxovirus RdRP inhibitor
|
GHP-88310 (EIDD-3608) is an orally efficacious, non-nucleoside, broad-spectrum orthoparamyxovirus RNA-dependent RNA polymerase (RdRP) inhibitor, shows broad-spectrum antiviral activities for HPIV3, Sendai virus (SeV), MeV, and related canine distemper virus (CDV) with EC50 of 0.53 uM, 1.03 uM and 1.71 uM respectively. |
| PC-27198 |
Agathisflavone
ToLCNDV inhibitor
|
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities, a natural inhibitor of tomato leaf curl New Delhi virus (ToLCNDV) suppressor proteins AV2, AC2, and AC4. |
| PC-27149 |
ZW-2038
Orthopoxvirus inhibitor
|
ZW-2038 is a potent antiviral compound against orthopoxviruses vaccinia virus (VACV), monkeypox virus (MPXV), and cowpox virus (CPXV), inhibits VACV replication inhibitor in primary HFFs with EC50 of 876 nM. |
| PC-26716 |
G671
Nipah virus RdRp inhibitor
|
G671 is a highly potent, effective inhibitor of Nipah virus (NiV) RNA-dependent RNA polymerase (RdRp). |
| PC-26469 |
MWAC-3475
ZIKV NS4B inhibitor
|
MWAC-3475 is a potent small molecule Zika virus (ZIKV) inhibitor targeting the viral protein NS4B with EC50 of 0.63 uM in CPE-based assays. |
| PC-26062 |
AS-136A
MeV RdRp inhibitor
|
AS-136A is a potent, non nucleoside inhibitor of measles virus (MeV) virus RNA-dependent RNA polymerase (RdRp) activity with EC50 of 12 nM against live MeV (strain Alaska) in virus titer reduction assays. |
| PC-26059 |
CN-716 hydrochloride
ZIKV NS3 protease inhibitor
|
CN-716 hydrochloride is a covalent, dipeptide boronic acid inhibitor of ZIKV NS3 protease catalytic site with IC50 of 0.5 uM. |
| PC-26058 |
CN-716
ZIKV NS3 protease inhibitor
|
CN-716 is a covalent, dipeptide boronic acid inhibitor of ZIKV NS3 protease catalytic site with IC50 of 0.5 uM. |
| PC-26057 |
IRBM-Z-2
ZIKV NS3 protease inhibitor
|
IRBM-Z-2 is a potent, non-competitive, allosteric inhibitor of ZIKV NS3 protease with binding KD of 21 nM (ZIKV NS2B-NS3 protease) and biochemical IC50 of 42 nM, potently inhibits both ZIKV viral replication (IC50=25 nM) and infectivity of ZIKV (CPE IC50=16 nM). |
| PC-26056 |
IRBM-Z-1
ZIKV NS3 protease inhibitor
|
IRBM-Z-1 is a non-competitive allosteric inhibitor of ZIKV NS3 protease with IC50 of 1.8 uM (wt NS2B-NS3 protease), exhibits ZIKV antiinfectivity activity in cell culture assays with EC50 of 6.25 uM. |
| PC-25193 |
CAPCA-1
CEN inhibitor
|
CAPCA-1 (Cpmpound B) a highly potent cap-dependent endonuclease (CEN) inhibitor, shows broad-spectrum antiviral activity against bunyavirus including Lassa virus (LASV), lymphocytic choriomeningitis virus (LCMV), and Influenza viruses. |
