| Cat. No. |
Product Name |
Information |
| PC-35382 |
Tecovirimat
Orthopoxvirus inhibitor
|
Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses. |
| PC-70240 |
OX-1
MeV entry inhibitor
|
OX-1 (Oxazole 1) small molecule, specific Measles virus (MeV) entry inhibitor with IC50 of 55 uM. |
| PC-28207 |
FMAU
Orthopoxvirus inhibitor
|
FMAU (D-FMAU) is a deoxythymidine nucleoside analog inhibiting herpes simplex virus, various cancers, hepatitis B virus, and Epstein-Barr virus, shows broad-spectrum anti-orthopoxvirus activity with EC50 of 1.99 uM and 30 nM for vaccinia virus (VACV) and monkeypox virus (MPXV) respectively. |
| PC-27445 |
MDOLL-0591
CHIKV nsP3 inhibitor
|
MDOLL-0591 is a selective inhibitor targeting chikungunya virus (CHIKV) nsP3 macrodomain with IC50 of 10 uM, shows antiviral activity against CHIKV in cell culture. |
| PC-27198 |
Agathisflavone
ToLCNDV inhibitor
|
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities, a natural inhibitor of tomato leaf curl New Delhi virus (ToLCNDV) suppressor proteins AV2, AC2, and AC4. |
| PC-26716 |
G671
Nipah virus RdRp inhibitor
|
G671 is a highly potent, effective inhibitor of Nipah virus (NiV) RNA-dependent RNA polymerase (RdRp). |
| PC-26469 |
MWAC-3475
ZIKV NS4B inhibitor
|
MWAC-3475 is a potent small molecule Zika virus (ZIKV) inhibitor targeting the viral protein NS4B with EC50 of 0.63 uM in CPE-based assays. |
| PC-26062 |
AS-136A
MeV RdRp inhibitor
|
AS-136A is a potent, non nucleoside inhibitor of measles virus (MeV) virus RNA-dependent RNA polymerase (RdRp) activity with EC50 of 12 nM against live MeV (strain Alaska) in virus titer reduction assays. |
| PC-26059 |
CN-716 hydrochloride
ZIKV NS3 protease inhibitor
|
CN-716 hydrochloride is a covalent, dipeptide boronic acid inhibitor of ZIKV NS3 protease catalytic site with IC50 of 0.5 uM. |
| PC-26058 |
CN-716
ZIKV NS3 protease inhibitor
|
CN-716 is a covalent, dipeptide boronic acid inhibitor of ZIKV NS3 protease catalytic site with IC50 of 0.5 uM. |
| PC-26057 |
IRBM-Z-2
ZIKV NS3 protease inhibitor
|
IRBM-Z-2 is a potent, non-competitive, allosteric inhibitor of ZIKV NS3 protease with binding KD of 21 nM (ZIKV NS2B-NS3 protease) and biochemical IC50 of 42 nM, potently inhibits both ZIKV viral replication (IC50=25 nM) and infectivity of ZIKV (CPE IC50=16 nM). |
| PC-26056 |
IRBM-Z-1
ZIKV NS3 protease inhibitor
|
IRBM-Z-1 is a non-competitive allosteric inhibitor of ZIKV NS3 protease with IC50 of 1.8 uM (wt NS2B-NS3 protease), exhibits ZIKV antiinfectivity activity in cell culture assays with EC50 of 6.25 uM. |
