PCSK9 (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofPCSK9 PCSK9

Cat. No.	Product Name	Information
PC-24525	AZD0780 PCSK9 inhibitor	AZD0780 (AZD-0780) is a potent, orally bioavailable inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with Kd of <200 nM, binds to a novel pocket in the PCSK9 C-terminal domain and does not affect the PCSK9-LDL receptor (LDLR) interaction.
PC-24178	PCSK9 inhibitor 3f PCSK9 inhibitor	PCSK9 inhibitor 3f is a small molecule, orally bioavailable inhibitor of PCSK9 that antagonizes PCSK9-LDLR interaction with IC50 of 537 nM.
PC-22461	E28362 PCSK9 inhibitor	E28362 is a novel small-molecule PCSK9 inhibitor, effectively binds to PCSK9 (SPR KD=14.8 uM) and disrupts the PCSK9-LDLR interaction, promotes the degradation of PCSK9 via the ubiquitin-proteasome pathway.
PC-21266	NYX-1492 PCSK9 inhibitor	NYX-1492 is a small molecule PCSK9 inhibitor, blocks PCSK9 binding with the LDLR, attenuates inflammation in vascular cells and tissue-engineered blood vessels (TEBVs).

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