| Cat. No. |
Product Name |
Information |
| PC-21446 |
Go 6983
PKC inhibitor
|
Go 6983 is a potent, pan-PKC inhibitor with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM against PKCα, PKCβ, PKCγ, PKCδ and PKCζ, respectively. |
| PC-20701 |
CRT0066854
aPKC inhibitor
|
CRT0066854 is a potent and selective chemical inhibitor of atypical PKC (protein kinase C) isoforms PKCζ and PKCι with IC50 of 639 nM and 132 nM, respectively. |
| PC-35396 |
Bryostatin 1
|
Bryostatin 1 (NSC 339555) is a macrocyclic lactone derived from a marine invertebrate, fuctions as an activator of PKC with high binding affinity (Ki=1.35 nM). |
| PC-63488 |
PKCiota-IN-51
|
PKCiota-IN-51 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.7 nM, >15-fold selectivity over PKC-α and PKC-β. |
| PC-63224 |
PKC beta II inhibitor H6
|
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM, extracted from patent WO 2008096260 A1 as compound example H6.. |
| PC-42969 |
Indolactam V
|
Indolactam V ((-)-Indolactam V) is an indole alkaloid tumor promoter that activates protein kinase C (PKC), binds to PKC regulatory domains of mouse skin PKCη and rat brain PKCγ with Ki values of 3.4 nM and 1 uM, respectively. |
| PC-62814 |
PKC-IN-7
|
PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM. |
| PC-62477 |
UCN-01
|
UCN-01 (7-Hydroxystaurosporine. |
| PC-61793 |
Rottlerin
|
Rottlerin (Mallotoxin. |
| PC-61296 |
OSU-2S
|
A non-immunosuppressive FTY720 analogue, PKCδ activator with higher antiproliferative potency with IC50 of 2.4, 2.4, and 3.5 uM in Huh7, Hep3B, and PLC5 cells, respectively. |
| PC-70263 |
Calphostin C
|
A potent, selective and photo-dependent inhibitor of PKC with IC50 of 50 nM. |
| PC-60366 |
PKC-IN-6c
|
A novel, potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM). |
