| Cat. No. |
Product Name |
Information |
| PC-49769 |
Diaplasinin
PAI-1 inhibitor
|
Diaplasinin (PAI-749) is a potent, selective antagonist of plasminogen activator inhibitor 1 (PAI-1) with IC50 of 154 nM (preservation of tPA activity) and Ki of 253 nM, blocks PAI-1 mediated inhibition of uPA with IC50 of 87 nM. |
| PC-49768 |
Tiplaxtinin
PAI-1 inhibitor
|
Tiplaxtinin (PAI-039) is a selective, orally active plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 2.7 uM and Kd of 0.48 uM. |
| PC-38547 |
AZ3976
PAI-1 inhibitor
|
AZ3976 is a small molecule inhibitor of plasminogen activator inhibitor type 1 (PAI-1) with IC50 of 26 uM in enzymatic chromogenic assay. |
| PC-35871 |
MDI-2268
|
MDI-2268 (MDI2268) is a small-molecule, in vivo-active inhibitor of plasminogen activator inhibitor type-1 (PAI-1), demonstrates excellent pharmacokinetics, potent activity against vitronectin-bound PAI-1 in vivo, and efficacy in murine model of venous thrombosis.. |
| PC-35664 |
ZK824859
|
ZK824859 (ZK-824859) is a potent, selective urokinase plasminogen activator (uPA) inhibitor with IC50 of 79 nM (human uPA), displays little to no inhibitory activity against tPA and Plasmin (IC50>1 uM). |
| PC-35440 |
Cenupatide
|
Cenupatide is an urokinase plasminogen activator receptor (uPAR) inhibitor for treating disorders associated altered cell migration, such as cancer.. |
| PC-62457 |
XR 5118
|
XR 5118 is a small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 3.5 uM, binds to PAI-1 and reduces plasma PAI-1 activity levels, promotes endogenous thrombolysis and inhibits thrombus accretion. |
| PC-61650 |
SK 216
|
SK 216 is a potent, selective inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 44 uM. |
