| Cat. No. |
Product Name |
Information |
| PC-24254 |
Rapaprotin
26S proteasome inhibitor
|
Rapaprotin is a selective apoptosis inducer in multiple myeloma cells (NCI-H929, IC50=156 nM) and 26S proteasome assembly inhibitor. |
| PC-22711 |
Up284
Rpn13 inhibitor
|
Up284 is a small molecule inhibitor of proteasome's 19S Regulatory Particle (RP) ubiquitin receptor RPN13 (ADRM1, hRPN13, or GP110), covalently binds RPN13 and induces rapid apoptosis in ovarian cancer cells. |
| PC-22710 |
RA475
Rpn13 inhibitor
|
RA475 is a small molecule inhibitor of proteasome's 19S Regulatory Particle (RP) ubiquitin receptor RPN13 (ADRM1, hRPN13, or GP110), binds to RPN13 and induces rapid apoptosis in ovarian cancer cells. |
| PC-22652 |
FHND6091
Proteasome inhibitor
|
FHND6091 is the prodrug of FHND6081, which is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities. |
| PC-22651 |
FHND6081
Proteasome inhibitor
|
FHND6081 is a potent, selective oral proteasome inhibitor, binds irreversibly to the β5 submit of the 20S proteasome and exerts anti-cancer activities. |
| PC-22061 |
hRpn13 inhibitor XL44
hRpn13 inhibitor
|
XL44 is a potent, specific hRpn13 (proteasome subunit hRpn13)-binding compound, binds to hRpn13 Pru domain, induces loss of hRpn13 Pru and hRpn13-dependent apoptosis. |
| PC-21189 |
TCL-Ester
Rpn-13 inhibitor
|
TCL-Ester is the cell-permeable derivative of TCL-1, a non-covalent ligand targeting the Pru domain of Rpn-13. |
