| Cat. No. |
Product Name |
Information |
| PC-49616 |
RET agonist BT18
|
RET agonist BT18 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function. |
| PC-49615 |
RET agonist BT13
|
RET agonist BT13 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function. |
| PC-49375 |
TPX-0046
RET inhibitor
|
TPX-0046 (TPX0046) is a potent, selective next-generation RET/SRC inhibitor, demonstrates low nanomolar potency against WT and 18 RET mutations/fusions, as well as SRC, and is VEGFR2/KDR-sparing. |
| PC-73416 |
Enbezotinib
RET inhibitor
|
Enbezotinib is a potent, selective inhibitor of RET kinase, inhibits the RET autophosphorylation and shows antineoplastic activity. |
| PC-35951 |
BLU-667 trans form
|
BLU-667 trans form is the trans form of BLU-667, which is a highly potent, selective, next generation RET inhibitor.. |
| PC-62829 |
RET-IN-23c
|
RET-IN-23c is a potent and selective RET kinase inhibitor with IC50 of 61.2 nM, shows no significant inhibitory effect against VEGFR-2 and KDR. |
| PC-61163 |
Pz-1
|
A potent, dual pan-RET/VEGFR2 kinase inhibitor with IC50s of <1 nM for all RET, RET V804M and VEGFR2. |
