Cat. No. |
Product Name |
Information |
PC-63207 |
NAB-14
GluN2C/2D modulator
|
NAB-14 is a potent, selective negative allosteric modulator of GluN2C/2D-containing NMDA receptors with IC50 of 580 nM, >800-fold selective over GluN2A/GluN2 receptors. |
PC-42958 |
PEAQX tetrasodium hydrate
|
PEAQX (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM). |
PC-42957 |
PEAQX
|
PEAQX (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM). |
PC-61911 |
Rislenemdaz mesylate
GluN2B antagonist
|
Rislenemdaz mesylate (MK 0657, CERC 301) is a potent, orally bioavailable, brain‐penetrant, NR2B-selective NMDA receptor (GluN2B) antagonist with Ki and IC 50 of 8.1 nM and 3.6 nM respectively, with no off-target activity. |
PC-61909 |
Rislenemdaz hydrochloride
GluN2B antagonist
|
Rislenemdaz (MK 0657, CERC 301) is a potent, orally bioavailable, brain‐penetrant, NR2B-selective NMDA receptor (GluN2B) antagonist with Ki and IC 50 of 8.1 nM and 3.6 nM respectively, with no off-target activity. |
PC-61864 |
Pesampator, PF-04958242
|
PF-04958242 (Pesampator) is a novel potent, selctive, and orally-active AMPA receptor (AMPAR) positive allosteric modulator (PAM) with Ki of 170 nM, EC50 of 370 nM. |
PN-30006 |
Isomangiferin
|
Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel. |
PC-61721 |
IDRA-21
AMPAR PAM
|
IDRA-21 is a positive allosteric modulator of the AMPA receptor (AMPAR). |
PC-61713 |
Tezampanel
|
Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor. |
PC-61501 |
NS-1209
AMPA antagonist
|
NS-1209 is a selective, water-soluble, in vivo long-lasting AMPA antagonist with Ki of 43 nM. |
PC-60899 |
LY 3130481
|
LY3130481 (CERC611) is a potent, selective, noncompetitive TARP γ8-associated AMPA receptors with IC50 of 65.3 nM (GluA1/TARP γ-8), with no activity for γ-2 (cerebellum) or other TARP members. |
PC-60772 |
UBP 296
|
UBP 296 (UBP296, UBP-296) is a potent, and selective GluR5-subunit containing kainate receptor antagonist with Kd of 1.09 uM. |