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A potent, selective S1P3 antagonist with Ki of 0.25 nM; displays selectivity over other S1..
A potent, selective S1P3 antagonist with Ki of 0.25 nM; displays selectivity over other S1..
A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-f..
RU-521 (RU.521, RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor..
The first orally available, small-molecule TNIK inhibitor with IC50 of 21 nM; also weakly ..
ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks..
ML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); bl..
A potent, selective, allosteric and orally bioavailable protein tyrosine phosphatase SHP2 ..
