New Products

• PC-38716

  SB-699551

  SB699551 is a potent, selective 5-HT5A receptor antagonist with pKi of 8.3, >100-fold sele..

• PC-73320

  FHD-286

  FHD-286 (FHD286) is a highly potent, selective, allosteric and orally available inhibitor ..

• PC-72378

  BMS-986242

  BMS-986242 (BMS986242) is a potent, selective IDO1 inhibitor with IC50 of 2 nM in cellular..

• PC-72331

  MRTX1133

  MRTX-1133 (MRTX1133) is a potent, selective and noncovalent inhibitor KRAS G12D with SPR K..

• PC-35864

  CSRM617

  CSRM617 (CSRM-617) is a small-molecule inhibitor of the transcription factor ONECUT2 (OC2)..

• PC-35785

  STING agonist diABZI compound 3

  STING agonist diABZI compound 3 is an amidobenzimidazole (ABZI)-based compound that functi..

• PC-35449

  Exicorilant

  Exicorilant (CORT125281, CORT-125281) is a potent, selective glucocorticoid receptor (GR) ..

• PC-60095

  SPM-242 racemate

  A potent, selective S1P3 antagonist with Ki of 0.25 nM; displays selectivity over other S1..

• PC-60094

  SPM-242

  A potent, selective S1P3 antagonist with Ki of 0.25 nM; displays selectivity over other S1..

• PC-60093

  PDE5-IN-6c

  A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-f..

• PC-60018

  RU-521

  RU-521 (RU.521, RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor..

• PC-42270

  NCB-0846

  The first orally available, small-molecule TNIK inhibitor with IC50 of 21 nM; also weakly ..

• PC-45718

  ML-241

  ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks..

• PC-45719

  ML-241 hydrochloride

  ML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); bl..

• PC-42129

  SHP-099 hydrochloride

  A potent, selective, allosteric and orally bioavailable protein tyrosine phosphatase SHP2 ..

• PC-42128

  SHP-099

  SHP-099 (SHP099) is a potent, selective, allosteric and orally bioavailable protein tyrosi..