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Chemical Structure : 7,8 Dihydroxyflavone
Catalog No.: PC-70345Not For Human Use, Lab Use Only.
A naturally occurring flavone that has been found to act as a potent and selective agonist of Trk B with Kd of 320 nM.
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A naturally occurring flavone that has been found to act as a potent and selective agonist of Trk B with Kd of 320 nM; demonstrates remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders; also possess antiestrogenic and antiproliferative activities; orally bioavailable and able to penetrate the blood–brain barrier.
| M.Wt | 254.238 | |
| Formula | C15H10O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. English AW, et al. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16217-22.
2. Liu X, et al. J Med Chem. 2010 Dec 9;53(23):8274-86.
3. Le Bail JC, et al. Cancer Lett. 1998 Aug 14;130(1-2):209-16.
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