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Chemical Structure : Alflutinib methanesulfonate
CAS No.: 2130958-55-1
Catalog No.: PC-35641Not For Human Use, Lab Use Only.
Alflutinib methanesulfonate (AST-2818) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $228 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | $858 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Alflutinib methanesulfonate (AST-2818) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.
| M.Wt | 664.705 | |
| Formula | C29H35F3N8O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate |
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1. PCT Int. Appl. (2017), WO 2017152707 A1 20170914.
2. PCT Int. Appl. (2017), WO 2017152706 A1 20170914.
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