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Chemical Structure : BI-1388
Catalog No.: PC-35032Not For Human Use, Lab Use Only.
BI-1388 is a potent, specific, macrocyclic inhibitor of HCV NS3 protease, inhibits viral replication for various HCV genotypes and for resistant mutants D168V and R155K.
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BI-1388 is a potent, specific, macrocyclic inhibitor of HCV NS3 protease, inhibits viral replication for various HCV genotypes and for resistant mutants D168V and R155K; BI-1388 was shown to be highly selective against other serine/cysteine proteases, binds to the active site of NS3 that is located in the shallow and broad protein-protein interaction surface of the protease- and the helicase domain of the enzyme.
| M.Wt | 819.975 | |
| Formula | C41H53N7O9S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tsantrizos YS, et al. Angew Chem Int Ed Engl. 2003 Mar 28;42(12):1356-60.
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