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Chemical Structure : CAMKK2 inhibitor 4t
Catalog No.: PC-63352Not For Human Use, Lab Use Only.
CAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5.
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CAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5.
CAMKK2 inhibitor 4t potently inhibits AMPK phosphorylation in a hypothalamus-derived cell line with pIC50 of 6.3; reduces food intake in rodent models.
| M.Wt | 480.612 | |
| Formula | C30H32N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Price DJ, et al. Bioorg Med Chem Lett. 2018 Apr 5. pii: S0960-894X(18)30223-3.
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