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CaMKII-IN-1

Chemical Structure : CaMKII-IN-1

CAS No.: 1208123-85-6

CaMKII-IN-1

Catalog No.: PC-45443Not For Human Use, Lab Use Only.

A potent and highly selective CaMKII inhibitor with IC50 of 63 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent and highly selective CaMKII inhibitor with IC50 of 63 nM; no inhibitory effect for CaMKIV, MLCK, p38α, Akt1, PKC etc; shows 25-fold higher potency than KN-93.

Physicochemical Properties

M.Wt 548.0988
Formula C29H30ClN5O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 54 mg/mL

Chemical Name/SMILES

Benzenesulfonamide, 3-chloro-2-methyl-N-[5,6,7,8-tetrahydro-2-[(2-phenylethyl)amino]-6-(phenylmethyl)pyrido[4,3-d]pyrimidin-4-yl]-

References

1. Asano S, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6696-8.

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