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Chemical Structure : Elamipretide
CAS No.: 736992-21-5
Catalog No.: PC-61855Not For Human Use, Lab Use Only.
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell type.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $328 | In stock | |
| 10 mg | $548 | In stock | |
| 25 mg | $988 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
Elamipretide prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function.
| M.Wt | 639.802 | |
| Formula | C32H49N9O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide |
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1. Thomas DA, et al. J Am Soc Nephrol. 2007 Jan;18(1):213-22.
2. Zhao K, et al. Biochem Pharmacol. 2005 Dec 5;70(12):1796-806.
3. Mizuguchi Y, et al. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1545-53.
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