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Chemical Structure : Flecainide
Catalog No.: PC-70213Not For Human Use, Lab Use Only.
A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart, slowing the upstroke of the cardiac action potential.
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A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart, slowing the upstroke of the cardiac action potential; also inhibits ryanodine receptor 2 (RyR2), reduces calcium sparks and thus arrhythmogenic calcium waves in the heart.
Heart Arrhythmia
Approved
| M.Wt | 414.343 | |
| Formula | C17H20F6N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hilliard FA, et al. J Mol Cell Cardiol. 2010 Feb;48(2):293-301.
2. Salvage SC, et al. Acta Physiol (Oxf). 2015 Jul;214(3):361-75.
3. Salvage SC, et al. Br J Pharmacol. 2017 Apr 3. doi: 10.1111/bph.13807.
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