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Chemical Structure : GBT601
Catalog No.: PC-20064Not For Human Use, Lab Use Only.
GBT601 (Osivelotor, GBT021601) is an oral, small molecule, next-generation sickle hemoglobin (HbS) polymerization inhibitor, increases hemoglobin-oxygen (Hb-O2) affinity and stabilizes Hb in the oxy-hemoglobin (oxyHb) state, thereby inhibiting polymerization of HbS in RBCs.
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GBT601 (Osivelotor, GBT021601) is an oral, small molecule, next-generation sickle hemoglobin (HbS) polymerization inhibitor, increases hemoglobin-oxygen (Hb-O2) affinity and stabilizes Hb in the oxy-hemoglobin (oxyHb) state, thereby inhibiting polymerization of HbS in RBCs.
| M.Wt | ||
| Formula | ||
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. R. Clark Clark Brown, et al. Blood. Volume 138, Supplement 1, 23 November 2021, Page 3099
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