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Chemical Structure : Jaceosidin
Catalog No.: PC-36080Not For Human Use, Lab Use Only.
Jaceosidin (4'-Demethyleupatilin, Jaseocidin) is a trihydroxyflavone that exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties.
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Jaceosidin (4'-Demethyleupatilin, Jaseocidin) is a trihydroxyflavone that exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties; promotes angiogenesis via activation of VEGFR2/FAK/PI3K/AKT/NF-κB signaling pathways in endothelial cells; shows selective suppression of proliferation (IC50 = 82.1 μM in HSC-3 cells and 97.5 μM in Ca9.22 cells) and accumulation of cells at the sub-G1 stage of the cell cycle, induces apoptotic cell death and inhibits the Akt pathway in oral cancer cells.
| M.Wt | 330.292 | |
| Formula | C17H14O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lee HG, et al. J Ethnopharmacol. 2005 Apr 26;98(3):339-43.
2. Han HY, et al. Evid Based Complement Alternat Med. 2018 May 13;2018:5765047.
3. Allison BJ, et al. Nat Prod Res. 2017 Mar;31(6):707-712.
4. Lee TH, et al. Exp Biol Med (Maywood). 2014 Oct;239(10):1325-34.
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