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Chemical Structure : MAC1
Catalog No.: PC-62405Not For Human Use, Lab Use Only.
MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
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MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
MAC1 induces the formation of additional microtubule nucleation centers, which allows kinesin Kif15-dependent bipolar spindle assembly in the absence of Eg5 activity.
| M.Wt | 247.338 | |
| Formula | C15H21NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Al-Obaidi N, et al. ACS Chem Biol. 2016 Jun 17;11(6):1544-51.
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