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NSC639829

Chemical Structure : NSC639829

CAS No.: 134742-19-1

NSC639829 (NSC-639829;NSC 639829)

Catalog No.: PC-60870Not For Human Use, Lab Use Only.

A potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization. .

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization.

Physicochemical Properties

M.Wt 470.327
Formula C21H20BrN5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-(dimethylamino)benzamide

References

1. Abdel-Aziz W, et al. Invest New Drugs. 2003 Nov;21(4):421-8.

2. Jain A, et al. AAPS PharmSciTech. 2003 Oct 15;4(4):E52.

3. Balcer-Kubiczek EK, et al. Cancer Chemother Pharmacol. 2007 May;59(6):781-7.

4. Hallur G, et al. J Med Chem. 2006 Apr 6;49(7):2357-60.

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