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NY-0123

Chemical Structure : NY-0123

CAS No.: 1801911-70-5

NY-0123 (NY0123)

Catalog No.: PC-63104Not For Human Use, Lab Use Only.

NY-0123 is a novel potent Exchange proteins directly activated by cAMP (EPAC) antagonist with IC50 of 0.9 and 2.4 uM for EPAC1 and EPAC2, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NY-0123 is a novel potent Exchange proteins directly activated by cAMP (EPAC) antagonist with IC50 of 0.9 and 2.4 uM for EPAC1 and EPAC2, respectively; NY0123 is more potent than ESI-09, and is a valuable pharmacological probes to facilitate our efforts in elucidating the biological functions of EPAC and developing potential novel therapeutics against human diseases.

Physicochemical Properties

M.Wt 399.656
Formula C16H13Cl3N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(5-tert-Butylisoxazol-3-yl)-2-oxo-N'-(3,4,5-trichlorophenyl)acetohydrazonoyl Cyanide

References

1. Ye N, et al. J Med Chem. 2015 Aug 13;58(15):6033-47.

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