You are here:Home-Chemical Inhibitors & Agonists-GPCR-Histamine Receptor-PF-3893787
PF-3893787

Chemical Structure : PF-3893787

CAS No.: 943057-12-3

PF-3893787 (Adriforant;ZPL-3893787;ZPL-389;PF-03893787)

Catalog No.: PC-61567Not For Human Use, Lab Use Only.

PF-3893787 (ZPL 3893787) is a potent and selective H4 receptor antagonist with binding Ki of 2.4 nM.

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Adriforant (PF-3893787, ZPL 3893787) is a potent and selective H4 receptor antagonist with binding Ki of 2.4 nM.
    Adriforant (PF-3893787, ZPL 3893787) has an IC50 of 1.16 nM on human native isolated eosinophils assessing actin polymerisation.
    Adriforant (PF-3893787, ZPL 3893787) exhibits anti-inflammatory activity.

    Physicochemical Properties

    M.Wt 262.361
    Formula C13H22N6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-N-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidine-2,4-diamine

    References

    1. Mowbray CE, et al. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: