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PSB-KD-107

Chemical Structure : PSB-KD-107

CAS No.: 955121-65-0

PSB-KD-107 (PSB-KD107)

Catalog No.: PC-49030Not For Human Use, Lab Use Only.

PSB-KD-107 is a potent, selective GPR18 receptor agonist, produces concentration-dependent relaxation in phenylephrine-precontracted endothelium-intact aortic rings with pIC50 of 5.22, exerts vascular activity and produces total relaxation of phenylephrine-pre-contracted rat aorta.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PSB-KD-107 is a potent, selective GPR18 receptor agonist, produces concentration-dependent relaxation in phenylephrine-precontracted endothelium-intact aortic rings with pIC50 of 5.22, exerts vascular activity and produces total relaxation of phenylephrine-pre-contracted rat aorta.

Physicochemical Properties

M.Wt 378.436
Formula C20H22N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9-(2-(1H-indol-3-yl)ethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione

References

1. Magdalena Kotańska, et al. Pharmaceuticals (Basel). 2021 Aug 13;14(8):799.

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