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Panx-1 blocker 15b

Chemical Structure : Panx-1 blocker 15b

CAS No.:

Panx-1 blocker 15b

Catalog No.: PC-72399Not For Human Use, Lab Use Only.

Panx-1 blocker 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Panx-1 blocker 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM.
Panx-1 blocker 15b (administered intrathecally, 1 nM) completely reverted the hypersensitivity in the mouse model of oxaliplatin-induced neuropa.

Physicochemical Properties

M.Wt 508.501
Formula C25H20N2O8S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Letizia Crocetti, et al. Eur J Med Chem. 2021 Nov 5;223:113650.

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