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Chemical Structure : S-38093
Catalog No.: PC-60377Not For Human Use, Lab Use Only.
A novel brain-penetrant H3 receptor antagonist/inverse agonist that shows procognitive properties in vivo.
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A novel brain-penetrant H3 receptor antagonist/inverse agonist that shows procognitive properties in vivo; induces synergistic memory-enhancing effect in mice combined with Donepezil; induces a reversal of age-dependent effects on hippocampal BDNF-IX, BDNF-IV and BDNF-I transcripts and increases vascular endothelial growth factor (VEGF) expression, increases adult hippocampal neurogenesis in vivo.
| M.Wt | 324.85 | |
| Formula | C17H25ClN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Panayi F, et al. Eur J Pharmacol. 2017 May 15;803:1-10.
2. Sors A, et al. Eur J Pharmacol. 2017 May 15;803:11-23.
3. Guilloux JP, et al. Sci Rep. 2017 Feb 20;7:42946.
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