Chemical Structure : SBI-668
Catalog No.: PC-20712Not For Human Use, Lab Use Only.
SBI-668 is a selective inhihitor of SHP2-E76K mutant with IC50 of 2.1 uM in isothermal CETSA assays, 7-fold selectivity over SHP2-WT (IC50=15 uM).
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SBI-668 is a selective inhihitor of SHP2-E76K mutant with IC50 of 2.1 uM in isothermal CETSA assays, 7-fold selectivity over SHP2-WT (IC50=15 uM).
M.Wt | 439.49 | |
Formula | C26H17NO4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Romero C, et al. J Biol Chem. 2020 Feb 28;295(9):2601-2613.
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