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Chemical Structure : Trabectedin
CAS No.: 114899-77-3
Catalog No.: PC-45909Not For Human Use, Lab Use Only.
Trabectedin (Ecteinascidin-743, ET-743, Ecteinascidin) is a marine alkaloid isolated from the Caribbean tunicate Ecteinascidia turbinata that shows remarkably anticancer activity in a variety of in vitro and in vivo systems.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $1680 | In stock | |
| 5 mg | Get quote |
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Trabectedin (Ecteinascidin-743, ET-743, Ecteinascidin) is a marine alkaloid isolated from the Caribbean tunicate Ecteinascidia turbinata that shows remarkably anticancer activity in a variety of in vitro and in vivo systems; a DNA minor groove, guanine-specific alkylating agent; shows hign potency against ovarian carcinoma xenografts.
Ovarian Cancer
Approved
| M.Wt | 761.8372 | |
| Formula | C39H43N3O11S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19-one, 5-(acetyloxy)-3',4',6,6a,7,13,14,16-octahydro-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-, (1'R,6R,6aR,7R,13S,14S,16 |
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1. Pommier Y, et al. Biochemistry. 1996 Oct 15;35(41):13303-9.
2. Valoti G, et al. Clin Cancer Res. 1998 Aug;4(8):1977-83.
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