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Visomitin

Chemical Structure : Visomitin

CAS No.: 934826-68-3

Visomitin (SKQ1 bromide;PDTP)

Catalog No.: PC-62577Not For Human Use, Lab Use Only.

Visomitin (SKQ1 bromide, PDTP) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).

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Biological Activity

Visomitin (SKQ1 bromide, PDTP) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).
Visomitin prevents neuronal loss and synaptic damage in a rat model of spontaneous Alzheimer’s disease, slows development of age-related ocular pathologies in murine, porcine, bovine, and canine model systems.

Physicochemical Properties

M.Wt 617.61
Formula C36H42BrO2P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(10-(4,5-dimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl)triphenylphosphonium bromide

References

1. Novikova YP, et al. Biochemistry (Mosc). 2014 Oct;79(10):1101-10.

2. Stefanova NA, et al. Aging (Albany NY). 2016 Oct 6;8(11):2713-2733.

3. Skulachev VP, et al. Biochem Biophys Res Commun. 2013 Nov 15;441(2):275-9.

4. Brzheskiy VV, et al. Adv Ther. 2015 Dec;32(12):1263-79.

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