| PC-25912 |
ABD0171
ALDH1A3 inhibitor
|
ABD0171 (ABD-0171) is a potent, selective and irreversible ALDH1A3 inhibitor with additional ALDH1A1 activity, disrupts key oncogenic pathways, including IL6/JAK/STAT3, tPA, and Src/FAK, resulting in robust antitumor and antimetastatic effects in vitro and in vivo. |