| Cat. No. |
Product Name |
Information |
| PC-45421 |
GLPG0492
SARM
|
GLPG0492 (GLPG-0492) is an orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM. |
| PC-42652 |
RU 58841
AR inhibitor
|
RU 58841 nonsteroidal, specific androgen receptor inhibitor, show potential for the topical treatment of androgen-dependent skin disorders such as acne, androgenetic alopecia and hirsutism. |
| PC-26742 |
DALTAC-1
AR-p300/CBP DALTAC
|
DALTAC-1 (JYZ3032, Domain-ALTeration Chimera 1) is a specific AR-p300/CBP Domain-ALTeration Chimeras (DALTAC), targets the AR-p300 complex by repurposing their natural interfaces to block activation of the AR oncogenic enhanceosome, selectively suppresses the growth of AR-positive prostate cancer cells. |
| PC-26659 |
T878A-mutant AR inhibitor S-94
T878A-mutant AR antagonist
|
T878A-mutant AR inhibitor S-94 is a selective androgen receptor T878A-mutant androgen receptor (AR) antagonist, inhibits AR transcriptional activity (IC50=0.38 μM) and suppresses cell proliferation (IC50=10.32 μM) in LNCaP cells harboring the T878A-mutant AR. |
| PC-25059 |
AZD3514
AR inhibitor
|
AZD3514 is an orally bioavailable small-molecule androgen receptor downregulator with pIC50 of 5.75, inhibits androgen-dependent and -independent AR signaling. |
| PC-25024 |
Dimethylcurcumin
AR inhibitor
|
Dimethylcurcumin (ASC-J9) is an androgen receptor degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion. |
| PC-24994 |
ADGRD1 agonist GL64
GPR133 agonist
|
ADGRD1 agonist GL64 is a selective agonist of ADGRD1/GPR133 with EC50 of 3.98 uM in CRE-luciferase assays in ADGRD1-overexpressing HEK293T cells. |
| PC-24653 |
R9-AR-PIP
PCNA/AR inhibitor
|
R9-AR-PIP is a small peptide mimicking androgen receptor (AR) PIP-box that inhibit the PCNA/AR interaction, inhibits the expression of AR target genes, AR transcriptional activity and the growth of AR-expressing cells, binds to GFP-PCNA with Kd of 2.73 uM in MST assays. |
| PC-24015 |
RU 58841
Androgen receptor antagonist
|
RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen, shows potential for androgen-dependent skin disorders such as acne, androgenetic alopecia and hirsutism. |
| PC-23465 |
AR antagonist BG-15n
AR antagonist
|
AR antagonist BG-15n is a novel small molecule androgen receptor (AR) antagonist, binds to the ligand-binding domain of AR, promotes AR localization to the nucleus, yet potently and selectively down-regulates AR-target genes. |
| PC-23464 |
AR antagonist BG-15a
AR antagonist
|
AR antagonist BG-15a is a novel small molecule androgen receptor (AR) antagonist, binds to the ligand-binding domain of AR, promotes AR localization to the nucleus, yet potently and selectively down-regulates AR-target genes. |
| PC-22862 |
AR modulator 1
SARM
|
AR modulator 1 is a potent, selective androgen receptor modulator (SARM). |
