Cat. No. |
Product Name |
Information |
PC-49412 |
EPI-7170
AR-NTD inhibitor
|
EPI-7170 is a potent next-generation analog of Ralaniten (EPI-002) and inhibitor of androgen receptor N-terminal domain (AR-NTD), inhibits androgen-induced PSA-luciferase activity in transiently transfected LNCaP cells with IC50 of 1.08 uM. |
PC-38370 |
Rezvilutamide
Androgen Receptor inhibitor
|
Rezvilutamide (SHR3680) is a novel and pure androgen-receptor (AR) antagonist that shows potent antitumor activity against castration-resistant prostate cancer (CRPC) but with much less brain distribution than enzalutamide. |
PC-73372 |
A4B17
BAG1L-AR NTD inhibitor
|
A4B17 is a small molecule that inhibits BAG1L-AR NTD interaction, inhibits the proliferation of AR positive prostate cancer cells. |
PC-73220 |
Pyrilutamide
AR antagonist
|
Pyrilutamide (KX826) is an androgen receptor (AR) antagonist and a potential first-in-class topical drug for the treatment of androgenetic alopecia (AGA) and acne vulgaris. |
PC-72512 |
JNJ-pan-AR
AR inhibitor
|
JNJ-pan-AR is a highly potent, selective antagonist of androgen receptor (AR) wild-type and F877L mutant for the treatment of the F877L mutant and wild-type CRPC. |
PC-35866 |
IMTPPE
|
IMTPPE (SID 3712502) is a novel small molecule capable of inhibiting androgen receptor (AR) transcriptional activity (IC50=1 uM) and protein level in C4-2 prostate cancer cells. |
PC-35497 |
Leelamine hydrochloride
|
Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells. |
PC-35346 |
RD162
|
RD162 is a second-generation, orally available antiandrogen that binds to androgen receptor (AR) with IC50 of 30.9 nM. |
PC-35143 |
LGD-2226
|
LGD-2226 (LGD2226) is an orally active, selective androgen receptor modulator (SARM) with binding Ki of 1 nM, >1000-fold selectivity over GR,PR, MR and ER. |
PC-35133 |
LY305
|
LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM). |
PC-35003 |
BAY 1024767
|
BAY 1024767 (BAY1024767) is a higly potent antagonist of androgen receptor (AR) wild-type (IC50=46 nM) and mutant forms located in the AR ligand-binding domain (LBD). |
PC-42895 |
BMS-564929
|
BMS-564929 is a potent, selective androgen receptor modulator (SARM) that binds to AR with Ki of 2.11 nM. |