| Cat. No. |
Product Name |
Information |
| PC-61861 |
LGD-3303
SARM
|
LGD-3303 is an orally available, brain-penetrant nonsteroidal selective androgen receptor modulator (SARM) that that shows little or no cross-reactivity with related nuclear receptors. |
| PC-61774 |
VPC14449
AR DBD inhibitor
|
VPC14449 (VPC-14449) is a potent and selective androgen receptor DNA-binding domain (AR-DBD) inhibitor with IC50 of 0.34 uM, without affecting AR protein expression. |
| PC-61678 |
EPI-001
AR NTD inhibitor
|
EPI-001 is a small molecule that blocks transactivation of the androgen Receptor (AR) NTD (IC50=6 uM) and specificly inhibits AR without attenuating transcriptional activities of related steroid receptors. |
| PC-61444 |
Metribolone
AR ligand
|
Metribolone (R1881) is an orally active anabolic-androgenic steroid and a 19-nortestosterone derivative that has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR. |
| PC-61086 |
BMS-641988
AR antagonist
|
BMS-641988 is a potent, selective, nonsteroidal androgen receptor antagonist with Ki of 1.7 nM, MDA-MB-453 cell IC50 of 16 nM. |
| PC-60530 |
Ralaniten acetate
AR-NTD inhibitor
|
Ralaniten acetate (EPI-506) is the acetate prodrug of Ralaniten (EPI-002), a small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer. |
| PC-60529 |
Ralaniten
AR-NTD inhibitor
|
Ralaniten (EPI-002) is a novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor, inhibits AR transcriptional activity with IC50 of 7.4 uM. |
| PC-70129 |
Proxalutamide
AR antagonist
|
Proxalutamide (GT-0918) is a potent androgen receptor (AR) antagonist with ability to down regulate AR protein level in prostate cancer cells. |
| PC-70118 |
LGD4033
SARM
|
LGD-4033 (VK-5211, Ligandrol) is a nonsteroidal, oral selective androgen receptor modulator (SARM), binds androgen receptor with high affinity (Ki=1 nM) and selectivity. |
| PC-45422 |
GLPG-0492 R enantiomer
|
The R enantiomer of GLPG-0492, a non-steroidal selective androgen receptor modulator (SARM) for treatment for Duchenne muscular dystrophy (DMD). |
| PC-45612 |
ORM-15341
AR inhibitor
|
ORM-15341 (Ketodarolutamide, BAY1896953) is the active main metabolite of ODM-201, a potent wt/mutant androgen receptor (AR) inhibitor, inhibits wtAR/AR(F876L) with IC50s of 25/51 nM respectively. |
| PC-45932 |
Enzalutamide
AR antagonist
|
Enzalutamide (MDV3100) is a potent, selective and orally available androgen-receptor (AR) antagonist with IC50 of 36 nM. |
