| Cat. No. |
Product Name |
Information |
| PC-28294 |
UBASHIN-2
UBASH3B inhibitor
|
UBASHIN-2 is a small-molecule inhibitor targeting UBASH3B 2HP domain, disrupts mitotic localization of UBASH3B and Aurora B, inducing arrest and cell death during mitosis. |
| PC-26460 |
ATC12
Aurora A-TPX2 inhibitor
|
ATC12 is a specific small molecule inhibitor of Aurora-A/TPX2 interactionwith IC50 of 25.6 uM, binds Aurora-A and to compete with TPX2. |
| PC-26261 |
NN-01-195
HSP90/AURKA inhibitor
|
NN-01-195 is a chimeric small molecule conjugate of HSP90 and AURKA inhibitor, tightly binds and inhibits both AURKA and HSP90 with IC50 of 3.1 nM and 8.1 nM in biochemical assays. |
| PC-22459 |
AurkinA
Aurora A inhibitor
|
AurkinA (Aurkin A) is a chemical inhibitor of the AURKA-TPX2 interaction and potent allosteric inhibitor of Aurora A (AURKA), shows binding affinity to AURKA with ITC Kd of 3.77 uM. |