| Cat. No. |
Product Name |
Information |
| PC-38096 |
NS3728
VRAC inhibitor
|
NS3728 (Emidurdar, SCO-101) is a potent volume-regulated anion channel (VRAC) blocker with IC50 of 460 nM. |
| PC-35990 |
T16Ainh-A01
TMEM16A inhibitor
|
T16Ainh-A01 is an inhibitor of the calcium-activated chloride channel TMEM16A, inhibits Ca2+-activated Cl− channel (CACC) activity in TMEM16A-transfected FRT cells with IC50 of 1 uM. |
| PC-35775 |
CLP290
KCC2 activator
|
CLP290 (CLP-290) is an orally acirtve small molecule K+-Cl- cotransporter isotype 2 (KCC2) activator, the carbamate prodrug of CLP257. |
| PC-35541 |
DRAinh-A250
SLC26A3 inhibitor
|
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
| PC-43155 |
IAA-94
Chloride channel inhibitor
|
IAA-94 (R(+)-Methylindazone) is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM. |
| PC-62452 |
OADS
CLC Chloride Channel inhibitor
|
OADS is a specific, reversible, small-molecule inhibitor directs against CLC (Chloride Channel) antiporter with Ki of 29 uM, has no specific effect on a CLC channel (ClC-1). |
| PC-62063 |
VU 0463271
KCC2 inhibitor
|
VU 0463271 is a potent, selecitve inhibitor of the neuronal K-Cl cotransporter KCC2 with IC50 of 61 nM. |
| PC-60024 |
CLP257
KCC2 activator
|
CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM. |
| PC-47506 |
Chlorotoxin
Chloride channel inhibitor
|
Chlorotoxin is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus). |
| PC-43124 |
Dichlorophen
TMEM16A inhibitor
|
Dichlorophen (DDM) is an anticestodal agent, fungicide, germicide, and antimicrobial agent, also blocks calcium-activated chloride channel (CaCC) TMEM16A with IC50 of 5.49 uM in HEK293 cells, shows no activity on ENaC or CFTR currents. |
| PC-25157 |
Fluralaner
GABA-Cls inhibitor
|
Fluralaner is a systemic insecticide and acaricide through potent blockage of GABA and L-glutamate gated chloride channels. |
| PC-25156 |
Tigolaner
GABA-Cls inhibitor
|
Tigolaner (BAY-1272858) is a potent, allosteric modulator/ inhibitor of GABA-gated chloride channels (GABA-Cls) with pIC50 of 9.0. |
