| Cat. No. |
Product Name |
Information |
| PC-27811 |
Lornoxicam
COX inhibitor
|
Lornoxicam (Chlortenoxicam, Ro 13-9297) is a highly potent antirheumatic agent and nonsteroidal anti-inflammatory drug (NSAID), shows inhibition of cyclooxygenase COX-1 and COX-2 with IC50 of 5 nM and 8 nM respectively. |
| PC-27810 |
Tenoxicam
COX-2 inhibitor
|
Tenoxicam (Ro12-0068) is a type 2 cyclooxygenase (COX-2) inhibitor and non-steroidal anti-inflammatory drug (NSAID). |
| PC-27809 |
Piroxicam
COX inhibitor
|
Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor with IC50 of 47 and 25 μM for human monocyte COX-1 and COX-2, respectively. |
| PC-27808 |
Isoxicam
COX inhibitor
|
Isoxicam is a nonselective inhibitor of COX-1 and COX-2, a non-steroidal anti-inflammatory drug (NSAID). |
| PC-27807 |
Sudoxicam
COX inhibitor
|
Sudoxicam is a nonsteroidal anti-inflammatory drug (NSAID) and cyclooxygenase (COX) inhibitor. |
| PC-27806 |
Meloxicam
COX-2 inhibitor
|
Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) and preferential cyclooxygenase-2 (COX-2) inhibitor with IC50 of 52.35 nM. |
| PC-27218 |
Phosphosulindac
Cyclooxygenase inhibitor
|
Phosphosulindac (Phospho-sulindac, OXT-328) is a sulindac derivative and potential anti-cancer and anti-inflammatory agent, is effective in colon cancer and non-small-cell lung cancer (NSCLC). |
| PC-27217 |
Sulindac
Cyclooxygenase inhibitor
|
Sulindac (MK-231) is a nonsteroidal anti-inflammatory drug (NSAID) and inhibitor of cyclooxygenase-1 (COX-1) and COX-2, inhibits tumor growth via COX-2 suppression, exhibits anti-proliferative and anti-invasive effects and enhances the sensitivity to paclitaxel in ovarian cancer. |
| PC-26768 |
Ketorolac
COX inhibitor
|
Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor with IC50 of 20 nM for COX-1 and 120 nM for COX-2, also is a DDX3 inhibitor. |
| PC-26605 |
LM-1685
COX-2 inhibitor, LMO7 inhibitor
|
LM-1685 is a potent and selective cyclooxygenase-2 (COX-2) inhibitor with IC50 of 0.65 uM for COX-2 from human monocytes, with limited acitivty for COX-1. |
| PC-26241 |
VA1213
COX-2 inhibitor
|
VA1213 is a selective cyclooxygenase-2 (COX-2) inhibitor with IC50 of 66.28 uM, suppresses tumor cells growth (HT-29 IC50=26.6 uM, 48h). |
| PC-26089 |
Epicatechin
COX-1 inhibitor
|
Epicatechin((-)-Epicatechin, (-)-Epicatechol) is a small molecule inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 3.2 uM, inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB, interacts with and neutralize reactive oxygen species (ROS) in cells. |
