Cat. No. |
Product Name |
Information |
PC-20874 |
Valdecoxib
COX-2 inhibitor
|
Valdecoxib (SC 65872) is a potent and selective inhibitor of COX-2 with IC50 of 5 nM, shows no activity against COX-1. |
PC-20873 |
Etoricoxib
COX-2 inhibitor
|
Etoricoxib (MK-0663) is a potent, selective and orally active inhibitor of COX-2 with IC50 of 1.1 uM for COX-2 (LPS-induced prostaglandin E2 synthesis), shows no activity against COX-1. |
PC-20235 |
SC-58125
COX-2 inhibitor
|
SC-58125 is a potent, selective inhibitor of COX-2 with IC50 of 0.05 uM, without inhibition on COX-1 (IC50>10 uM). |
PC-20195 |
Lumiracoxib
COX-2 inhibitor
|
Lumiracoxib (COX-189) is a highly selective COX-2 inhibitor with IC50 of 0.14 uM in COX-2-expressing dermal fibroblasts, inhibits purified COX-2 with Ki of 0.06 uM, 50-fold selectivity over COX-1 (Ki=3 uM). |
PC-63065 |
Polmacoxib
|
Polmacoxib (CG-100649) is a novel NSAID proposed to inhibit both COX-2 and carbonic anhydrase (CA)-I/-II. |
PC-62881 |
Chemocoxib A
|
Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively. |
PC-62672 |
Tilmacoxib
|
Tilmacoxib (JTE-522) is a potent, selective inhibitor of cyclooxygenase-2 (COX-2) that inhibits human recombinant COX-2 with IC50 of 85 nM, dispalys no activity against COX-1 (IC50>100 uM). |
PC-61664 |
SC-236
|
SC-236 (SC58236) is a potent, selective, orally active inhibitor of COX-2 with IC50 of 10 nM. |
PC-61415 |
Vitacoxib
|
A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL). |
PC-45292 |
Ampiroxicam
|
The prodrug of piroxicam that is a nonsteroidal anti-inflammatory drug (NSAID).. |
PC-45921 |
Acetaminophen
|
A well-known analgesic and antipyretic agent that selectively inhibits COX activities in the brain. |
PC-45313 |
Deracoxib
|
A selective COX-2 inhibitor that is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).. |