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Cat. No. Product Name Information
PC-72428

ASN007

ERK inhibitor

ASN007 (ASN-007) is a potent, selective, orally bioavailable ERK1/2 inhibitor with IC50 of 2 nM against both.
PC-72401

ASTX029

ERK inhibitor

ASTX029 (ASTX-029) is a highly potent, selective dual-mechanism ERK inhibitor with IC50 of <3 nM for ERK1/2, inhibits both ERK catalytic activity and the phosphorylation of ERK by MEK.
PC-72141

JWG-071

ERK5 inhibitor

JWG-071 is a selective Erk5 inhibitor (IC50<20 nM) with reduced Brd4/BET inhibitory activity.
PC-35813

CC-90003

CC-90003 (CC90003) is a potent and selective, covalent ERK1/2 inhibitor with IC50 of 10-20 nM, demonstrates excellent selectivity in a 258-kinase biochemical assay panel.
PC-35332

BAY-885

BAY-885 (BAY885) is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM, shows high selectivity over a panel of 357 kinases (Eurofins panel).
PC-63271

AZD0364

ERK1/2 inhibitor

Tizaterkib (AZD0364) is a potent, selective, ATP competitive, orally active ERK1/2 inhibitor with IC50 of 0.66 nM in ERK2 biochemical assay, binds similarly to ERK1 and ERK2 with Ki of 3.9 and 3.8 nM.
PC-42937

FR 180204

ERK1/2 inhibitor

FR 180204 is a potent, selective, ATP-competitive ERK inhibitor with Ki of 0.31 and 0.14 uM for ERK1 and ERK2, respectively.
PC-62596

MK-8353 hydrochloride

MK-8353 hydrochloride (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively.
PC-62595

MK-8353

MK-8353 (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively.
PC-61978

KO-947

KO-947 (KO947) is a potent and selective inhibitor of ERK1/2 kinase in biochemical, cellular and in vivo antitumor activity assays.
PC-61973

LY-3214996

Temuterkib (LY-3214996) is a novel potent, selective, orally active ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays.
PC-20223

Ulixertinib hydrochloride

ERK inhibitor

Ulixertinib hydrochloride (BVD-523) is a potent, selective, reversible, ATP-competitive ERK1/2 inhibitor with Ki of 0.3/0.04 nM, respectively.

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