Cat. No. |
Product Name |
Information |
PC-72428 |
ASN007
ERK inhibitor
|
ASN007 (ASN-007) is a potent, selective, orally bioavailable ERK1/2 inhibitor with IC50 of 2 nM against both. |
PC-72401 |
ASTX029
ERK inhibitor
|
ASTX029 (ASTX-029) is a highly potent, selective dual-mechanism ERK inhibitor with IC50 of <3 nM for ERK1/2, inhibits both ERK catalytic activity and the phosphorylation of ERK by MEK. |
PC-72141 |
JWG-071
ERK5 inhibitor
|
JWG-071 is a selective Erk5 inhibitor (IC50<20 nM) with reduced Brd4/BET inhibitory activity. |
PC-35813 |
CC-90003
|
CC-90003 (CC90003) is a potent and selective, covalent ERK1/2 inhibitor with IC50 of 10-20 nM, demonstrates excellent selectivity in a 258-kinase biochemical assay panel. |
PC-35332 |
BAY-885
|
BAY-885 (BAY885) is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM, shows high selectivity over a panel of 357 kinases (Eurofins panel). |
PC-63271 |
AZD0364
ERK1/2 inhibitor
|
Tizaterkib (AZD0364) is a potent, selective, ATP competitive, orally active ERK1/2 inhibitor with IC50 of 0.66 nM in ERK2 biochemical assay, binds similarly to ERK1 and ERK2 with Ki of 3.9 and 3.8 nM. |
PC-42937 |
FR 180204
ERK1/2 inhibitor
|
FR 180204 is a potent, selective, ATP-competitive ERK inhibitor with Ki of 0.31 and 0.14 uM for ERK1 and ERK2, respectively. |
PC-62596 |
MK-8353 hydrochloride
|
MK-8353 hydrochloride (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively. |
PC-62595 |
MK-8353
|
MK-8353 (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively. |
PC-61978 |
KO-947
|
KO-947 (KO947) is a potent and selective inhibitor of ERK1/2 kinase in biochemical, cellular and in vivo antitumor activity assays. |
PC-61973 |
LY-3214996
|
Temuterkib (LY-3214996) is a novel potent, selective, orally active ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. |
PC-20223 |
Ulixertinib hydrochloride
ERK inhibitor
|
Ulixertinib hydrochloride (BVD-523) is a potent, selective, reversible, ATP-competitive ERK1/2 inhibitor with Ki of 0.3/0.04 nM, respectively. |