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Cat. No. Product Name Information
PC-45741

JNJ-63533054

GPR139 agonist

 JNJ-63533054 (JNJ63533054) is a potent, selective GPR139 agonist that specifically activates human GPR139 in the calcium mobilization with EC50 of 16 nM.
PC-72146

TAK-041

GPR139 agonist

 TAK-041 (NBI-1065846) is a potent, selective, brain-penetrant GPR139 agonist with EC50 of 22 nM (CHO-T-REx Ca2+ assays), Ki of 119 nM.
PC-36128

GPR139 agonist AC4

GPR139 agonist AC4 is a novel small molecule GPR139 receptor agonist with EC50 of 220 nM in calcium mobilization assay in CHO-GPR139 cells. .
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