| Cat. No. |
Product Name |
Information |
| PC-49483 |
MLT-943
MALT1 inhibitor
|
MLT-943 is a potent and selective MALT1 protease inhibitor with IC50 of 40 nM in IL-2 reporter gene assay (Jurkat T cells), inhibits human PBMC IL-2 release with IC50 of 74 nM. |
| PC-49482 |
MLT-985
MALT1 inhibitor
|
MLT-985 (MLT985) is a potent, highly selective allosteric MALT1 inhibitor with biochemical IC50 of 3 nM, and 20 nM in IL-2 reporter gene assay (Jurkat T cells). |
| PC-49481 |
MLT-827
MALT1 inhibitor
|
MLT-827 is a potent and selective inhibitor of MALT1 paracaspase activity with IC50 of 5 nM. |
| PC-49480 |
MLT-231
MALT1 inhibitor
|
MLT-231 (MLT231) is a highly potent, selective, allosteric MALT1 inhibitor with biochemical IC50 of 9 nM, inhibits MALT1 cleavage of the BCL10 substrate with IC50 of 0.16 uM. |
| PC-49475 |
z-VRPR-fmk
MALT1 inhibitor
|
z-VRPR-fmk is a tetrapeptide inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) with Ki of 0.14 uM, shows complete inhibition at 1.25 uM. |
| PC-49440 |
RGT-068A
MALT1 inhibitor
|
RGT-068A is a potent selective MALT1 inhibitor. |
| PC-36043 |
MLT-747
MALT1 inhibitor
|
MLT-747 (MLT747) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 14 nM. |
| PC-36042 |
MLT-748
MALT1 inhibitor
|
MLT-748 (MLT748) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 5 nM, does not show inhibitory activity against 22 other tested human proteases (IC50>100 uM). |
| PC-42938 |
MALT1 inhibitor MI-2
MALT1 inhibitor
|
MALT1 inhibitor MI-2 is a selective, irreversible MALT1 paracaspase inhibitor with IC50 of 5.84 uM, displays little activity against the related caspase family members caspase-3, -8, and -9. |
| PC-22030 |
ABBV-MALT1
MALT1 inhibitor
|
ABBV-MALT1 is a potent, selective, allosteric inhibitor of the MALT1 paracaspase with binding KD of 37 nM, exhibits potent biochemical inhibition of MALT1 protease activity with IC50 of 349 nM. |
| PC-20142 |
MALT1 inhibitor 37
MALT1 inhibitor
|
MALT1 inhibitor 37 is a potent, selective and oral bioavailable MALT1 inhibitor with IC50 of 93 nM, shows high potency for inhibiting IL-2 production with IC50 of 1.4 uM. |
| PC-49479 |
MALT1 inhibitor 8
MALT1 inhibitor
|
MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1. |
