| Cat. No. |
Product Name |
Information |
| PC-49060 |
TCMCB07
MC4R antagonist
|
TCMCB07 is a synthetic, cyclic nonapeptide peptide antagonist of the melanocortin-4 receptor (MC4R), ameliorates cancer- and chronic kidney disease-associated cachexia. |
| PC-36115 |
RO 27-3225
|
RO 27-3225 (RO27-3225, RO 273225) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM, >30-fold selectivity over MC3R. |
| PC-35970 |
JNJ-10229570
|
JNJ-10229570 (JNJ10229570) is a novel potent, selective melanocortin receptor MC1R and MC5R antagonist with binding IC50 of 270 nM and 200 nM, respectively. |
| PC-61574 |
ML00253764 hydrochloride
|
ML00253764 is a non-peptide, brain penetrant melanocortin MC4 receptor (MC4R) antagonist with IC50 of 0.32, 0.81 and 2.12 uM for MC4, MC3 and MC5 receptors, respectively. |
| PC-61572 |
BL-6020 979
|
BL-6020/979 (SNT207979) is an orally available, selective, potent MC4R antagonist with IC50 of 19 nM. |
| PC-61571 |
MCL0129 tetrahydrochloride
|
MCL0129 is a selective, potent melanocortin-4 receptor (MC4R) antagonist with Ki of 7.9 nM, without affinity for MC1 and MC3. |
| PC-61570 |
MCL0129
|
MCL0129 is a selective, potent melanocortin-4 receptor (MC4R) antagonist with Ki of 7.9 nM, without affinity for MC1 and MC3. |
| PC-70138 |
Bremelanotide
|
A peptide, non-selective melanocortin receptor agonist for treatment for female sexual dysfunction. |
| PC-70060 |
THIQ
|
A potent and selective melanocortin 4 receptor (MC4R) agonist with EC50 of 2.1 nM. |
| PC-70059 |
SHU-9119
|
A potent melanocortin MC3 and MC4 receptor antagonist with IC50 of 0.23 nM and 0.06 nM, respectively. |
