| Cat. No. |
Product Name |
Information |
| PC-61237 |
MLE-4901
NK3R inhibitor
|
Pavinetant (MLE4901, AZD-2624) is a potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of menopausal hot flushes. |
| PC-70195 |
Fezolinetant
NK3R inhibitor
|
Fezolinetant (ESN-364) is a potent, selective, orally active neurokinin-3 receptor (NK3R) antagonist with pIC50/pKi of 7.7/7.6. |
| PC-42185 |
Aprepitant
NK-1 receptor inhibitor
|
Aprepitant (MK-0869) is a potent, orally active, long-acting human NK-1 receptor (substance P receptor) antagonist with IC50 of 0.09 nM. |
| PC-21757 |
Elinzanetant
NK1/3R inhibitor
|
Elizanetant (NT-814) is an orally active, selective neurokinin (NK) receptors 1 and 3 antagonist, modulates reproductive hormone secretion. |
| PC-21365 |
Talnetant
NK3R inhibitor
|
Talnetant (SB223412) is a potent, selective, competitive and brain-permeable neurokinin-3 receptor (NK3R) antagonist with Ki of 1.4 nM in hNK-3-CHO cells. |
| PC-38599 |
Tradipitant
NK1R antagonist
|
Tradipitant (VLY-686, LY686017) is a selective, orally bioavailable, centrally-acting neurokinin-1 receptor (NK1) antagonist with potential anti-emetic, anti-pruritic and anti-inflammatory activities. |
| PC-35774 |
NY0128
|
NY0128 (NY 0128) is a small molecule neuromedin U receptor 2 (NMUR2) with EC50 of 29.99 uM for hNMUR1 and 10.30 uM for hNMUR2 in intracellular calcium mobilization assays. |
| PC-35773 |
NY0116
|
NY0116 (NY 0116) is a small molecule neuromedin U receptor 2 (NMUR2) with EC50 of 27.76 uM for hNMUR1 and 13.61 uM for hNMUR2 in intracellular calcium mobilization assays. |
| PC-63390 |
Serlopitant
|
Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.. |
| PC-63134 |
Senktide
|
Senktide is a potent, selective agonist of neuromedin K3 (NK3) receptor (EC50 =0.5-3 nM), less potently agonizes the NK1 receptor (EC50=35 µM) and is without effect on the NK2 receptor.. |
| PC-63098 |
GR-64349
|
GR-64349 is a potent and selective tachykinin NK2 receptor agonist with EC50 of 3.7 nM, displays >1000- and >300-fold selectivity over NK1 and NK3 receptors, respectively.. |
| PC-62979 |
Maropitant citrate
|
Maropitant citrate (Cerenia) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs.. |
