Cat. No. |
Product Name |
Information |
PC-45701 |
BMS-202
PD-1/PD-L1 inhibitor
|
BMS-202 (PCC0208025) is a small molecule inhibitor of the PD-1/PD-L1 interaction with IC50 of 18 nM in a homogenous time-resolved fluorescence binding assay. |
PC-45776 |
BMS-1
PD-1/PD-L1 inhibitor
|
BMS-1 (PD1/PD-L1 inhibitor 1) is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay. |
PC-24461 |
AX-0085
IFN-γ inhibitor, PD-L1 expression inhibitor
|
AX-0085 is a specific PD-L1 expression inhibitor, blocks the IFN-γ-induced activation of JAK2/STAT1 pathway and up-regulation of PD-L1. |
PC-22369 |
PD-L1/CD73 inhibitor CC5
Dual PD-L1/CD73 inhibitor
|
PD-L1/CD73 inhibitor CC5 is a potent, dual PD-L1/CD73 inhibitor with IC50 of 6 nM/773 nM for PD-L1/CD73, respectively. |
PC-21925 |
SMC18
PD-L1 inhibitor
|
SMC18 is a specific small molecule CD47/SIRPα and PD-1/PD-L1 dual inhibitor, effectively blocks the CD47/SIRPα and PD-1/PD-L1 interactions with IC50 of 17.8 and 19.7 uM (human SIRPα and hPD-L1) respectively. |