Polo-like Kinase (PLK) compound (inhibitors, antagonists, modulators)-ProbeChem.com

Request The Product List ofPolo-like Kinase (PLK) Polo-like Kinase (PLK)

Cat. No.	Product Name	Information
PC-21081	Allopole PLK1 PBD inhibitor	Allopole is the first allosteric, specfic and cell-permeable inhibitor of the noncatalytic polo-box domain (PBD) of PLK1 (Polo-like kinase 1), Allopole is the prodrug of Allopole-A.
PC-21080	Allopole-A PLK1 PBD inhibitor	Allopole-A is the first allosteric, specfic inhibitor of the noncatalytic polo-box domain (PBD) of PLK1 (Polo-like kinase 1) with IC50 of 2.5 nM in FP-based assays, Allopole-A is the active form of Allopole.
PC-20477	MCC1019 PLK1 PBD inhibitor	MCC1019 is a selective inhibitor of PLK1, targets PLK1 Polo box domain (PBD) with binding IC50 of 16.4 uM, 2.75-fold over PLK2-PBD (IC50=44.1 uM) and > 6-fold higher specificity over PLK3 PBD (IC50 >100 uM).

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