| Cat. No. |
Product Name |
Information |
| PC-49418 |
Ogremorphin-1
GPR68 inhibitor
|
Ogremorphin-1 (OGM1) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.16 uM. |
| PC-49417 |
Ogremorphin
GPR68 inhibitor
|
Ogremorphin (OGM, OGM8345) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.71 uM. |
| PC-72990 |
MS48107
GPR68 PAM
|
MS48107 (MS 48107) is a potent, selective, positive allosteric modulator of G protein-coupled receptor 68 (GPR68, Log(αβ/KB)=6.83). |
| PC-61084 |
Ogerin
|
Ogerin (ZINC 67740571) is a selective GPR68 positive allosteric modulator (pEC50=6.83) with minimal PAM activity at the related proton-sensing GPCRs GPR4 and GPR65. |
| PC-61082 |
GPR4 antagonist 3b
GPR4 antagonist
|
GPR4 antagonist 3b is the first potent and selective proton-sensing GPCR GPR4 antagonist with IC50 of 67 nM, with no activity against TDAG8 and OGR1 (IC50>10 uM). |
| PC-20836 |
GPR4 antagonist 39c
GPR4 antagonist
|
GPR4 antagonist 39c is a potent and orally active GPR4 antagonist with IC50 of 110 nM. |
| PC-20835 |
NE 52-QQ57
GPR4 antagonist
|
NE 52-QQ57 (GPR4 antagonist 13) is a potent, elective, and efficacious GPR4 antagonist with IC50 of 70 nM (hGPR4). |
| PC-42974 |
ISX-9
|
ISX-9 (Isoxazole 9) is a isoxazole stem cell-modulator small molecule and GPR68 ligand through a chemical biology-target discovery strategy to GPR68, a proton (pH) sensing G protein-coupled receptor. |
