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Request The Product List ofRibosomal S6 Kinase (RSK) Ribosomal S6 Kinase (RSK)

Cat. No. Product Name Information
PC-49024

PF-4708671

S6K1 inhibitor

PF-4708671 is a potent, specific, cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), inhibits the activity of full-length S6K1 in vitro with Ki of 20 nM, and S6K1 isolated from IGF1-stimulated HEK293 cells with IC50 of 160 nM.
PC-72701

S6K2 inhibitor Compound 2

S6K2 inhibitor

S6K2 inhibitor Compound 2 is the first potent and highly isoform-specific S6K2 inhibitor with IC50 of 22 nM, inactive for the closely related isoform S6K1 at 5 uM.
PC-72284

PMD-026

RSK inhibitor

PMD-026 (PMD026) is an oral, reversible small molecule inhibitor of ribosomal S6 kinases (RSK1-4) with IC50 of 2 nM (RSK1), 0.7 nM (RSK2), 0.9 nM (RSK3) and 2 nM (RSK4).
PC-43059

LY-2584702 tosylate salt

LY-2779964 (LY2584702 tosylate) is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM.
PC-62045

BRD 7389

RSK inhibitor

BRD 7389 is an inhibitor of ribosomal S6 kinases (RSK) with IC50 of 1.5 uM, 2.4 uM, and 1.2 uM for RSK1, RSK2, and RSK3, respectively.
PC-45677

LJH-685

RSK inhibitor

LJH-685 is a potent and specific pan-RSK inhibitor with IC50s of 6 nM,5 nM and 4 nM for RSK1,RSK2 and RSK3 respectively.
PC-45919

CMK

CMK is an irreversible inhibitor of the CTD of RSK2 with similar potency as Fmk, also potently inhibits a Fyn mutant in which Val285 was replaced with Cys (IC50=1 nM).
PC-42627

BI-D1870

RSK inhibitor

BI-D1870 is a potent, specific ATP-competitive inhibitor of RSK isoforms with IC50 of 10-30 nM for RSK1/2/3/4.
PC-21764

BIX 02565

RSK2 inhibitor

BIX 02565 is a potent, selective ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1 nM.
PC-43060

LY-2584702 hydrochloride

LY2584702 is a potent, selective, ATP-competitive inhibitor of P70S6 kinase-1 (p70S6K1) with IC50 of 4 nM.
PC-43058

LY-2584702 free base

LY2584702 is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM.
PC-62854

RSK2-IN-20

RSK2-IN-20 is a potent, selective, and durable inhibitpr of RSK2 with IC50 of 47 nM.

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